Scientist / Sr. Scientist - Upstream - Technical Services - Manufacturing Sciences Laboratory

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Owing to the continuous growth of our Monoclonal pipeline of products, Eli Lilly & Company has invested in a new facility in Ireland, Lilly Limerick. To support this exciting new investment and meet the requirements of a safe and successful start-up, we are eager for talented individuals to join our team(s) and contribute to establishing Lilly Limerick as a reliable supplier of our innovative medicines and our goal of making a difference to people’s lives.

If you are looking for a challenging, rewarding career and feel you meet the requirements listed below we would love to consider you for a role at Lilly, Limerick.

Upstream Scientist - Technical Services/Manufacturing Sciences Laboratory

The TS/MS Upstream Scientist will provide direct technical support in the TS/MS laboratory. The successful applicant will have technical expertise in laboratory scale models for upstream operations and demonstrate strong data-driven decision-making and problem-solving capabilities. They will work to continuously improve process efficiency by implementing new technologies and process improvements in addition to investigation support. This role will incorporate the use of data analytics and process analytical technology to support the next generation bioprocessing facility in laboratory scale models to drive process development.

Key Responsibilities

• Have an in-depth knowledge of the science of biotech manufacturing and associated laboratory models and analytical tests, supporting upstream processing.

• Expertise in laboratory scale equipment operation and trouble shooting.

• Understand molecule-specific control strategy and basis of specifications and critical quality attributes.

• Work with the network and development organizations to ensure a well-understood, robust and fit-for-purpose laboratory models are developed and transferred. This will include those specific to the NGB processing including implementation of process analytical technologies in support of multivariate analyses and process modelling.

• Experience with the application of Raman spectroscopy integration into mammalian cell culture bioreactors

• Leading laboratory investigations in support of production operations.

• Support the design and start-up of the laboratory including equipment configuration and purchase, development of the laboratory data management strategy, establishment of laboratory protocols

• Support a laboratory startup plan in alignment with the health, safety and environmental team to ensure safe startup and operation.

• Create and review documents including laboratory SOPs, material specifications, protocols, and work instructions

• Establish partnerships to enable cross functional work with the quality control laboratory and other Lilly sites to ensure facility startup objectives are met.

• Understand basic statistical methodologies and statistically based experimental design.

• Identify process improvements and participate in implementation of Lean manufacturing initiatives

• Contribute to the authorship and review of regulatory submissions and responses to regulatory agencies

Basic Requirements:

• PhD degree based in biology, chemistry, biochemistry or similar discipline. MSc or BSc with equivalent experience may also be considered.
• Experience (>2 yrs) working in pharmaceutical laboratory and GMP manufacturing environments.

Additional Requirements:

• Demonstrated technical capability with high productivity
• Proven track record of curiosity with learning agility
• Self-starter with high initiative and data-driven approach to problem-solving
• Demonstrated strong interpersonal skills
• Demonstrated strong verbal and written communication skills
• Demonstrated adaptability and flexibility to working in different environments, teams etc.
• Demonstrated ability to participate in and facilitate decision-making
• Proficient in English

Work Environment:

• These are 8-hour day roles. As a manufacturing support function, the need for occasional evening or weekend support can arise.
• Although expected to be minimal, occasional travel is possible including to other Lilly sites both in- and outside of Ireland.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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