Sr Principal Scientist - Clinical Imaging

The Senior Principal Scientist is responsible for spearheading the imaging biomarker strategy and implementation across cardiovascular and metabolic indications in early- and late-phase clinical trials. This role involves collaboration with cross-functional study teams where you will lead the design of complex imaging approaches to test the efficacy and safety of Regeneron products. In this role, you will be responsible for developing and validating novel imaging-based biomarkers to address the needs of the Regeneron experimental therapies.

As a Senior Principal Scientist in Clinical Imaging you will:

• Collaborate closely with Research and Global Development colleagues to formulate appropriate imaging biomarker strategies to inform and advance the Regeneron clinical pipeline.
• Provide leadership during the strategy phase of study design, guiding the team on all imaging aspects of the study, presenting the imaging components of the integrated biomarker strategy to senior management for endorsement, and authoring of key study documents.
• Work closely with Clinical Imaging Operations and Clinical Trial Management to ensure the delivery of high-quality imaging data in clinical studies. This includes drafting imaging manuals and other documents for the trial, supporting the clinical team during the study start-up phase, and monitoring data integrity throughout the trial.
• Supervise imaging Clinical Research Organizations (CROs) to ensure execution of imaging components in the trial, timely address any image quality issues, and ensure flawless delivery of key study imaging data and achievements
• Identify gaps in imaging assessments for particular indications and propose novel biomarkers, and spearhead validation through collaboration with other functions within Regeneron or external institutions.
• Support regulatory submission packages as the imaging subject matter expert

This role requires that you:

• Work efficiently in a fast-paced, collaborative environment
• Communicate extremely effectively across clinical teams and functions, and with senior management
• Possess a broad knowledge of imaging and understand the challenges of image standardization across sites and countries
• Have strong analytical and problem-solving skills
• Thrive in addressing complex problems with innovative methods

To be considered for this position, we expect you to have completed a PhD or MD/PhD program, with a minimum of 6 years of experience in clinical imaging, specifically within cardiovascular and/or metabolic domains. We believe you should have extensive expertise in the acquisition and analysis of various imaging modalities, including MRI, CT, ultrasound, and echocardiography. While experience in industry-sponsored clinical trials is preferred, it is not mandatory.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location.  In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.  For other countries’ specific benefits, please speak to your recruiter.Please be advised that at Regeneron, we believe we are most successful and work best when we are together.  For that reason, many of Regeneron’s roles are required to be performed on-site.  Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.  

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions.  For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process.  Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$148,300.00 - $241,900.00